ICD 10 Code for HFrEF: The Complete 2026 Coding Guide

ICD 10 Code for HFrEF: The Complete 2026 Coding Guide
Last Updated: 25 Feb, 2026

The official ICD 10 code for HFrEF (Heart Failure with Reduced Ejection Fraction) is classified under the I50.2x category. This specific ICD-10 code for hfref identifies a chronic, progressive condition where the left-ventricular ejection fraction is 40% or lower. Using a precise ICD-10-CM code for HFrEF ensures that medical claims accurately reflect clinical necessity and qualify for guideline-directed therapies.

Accurate documentation is critical for successful medical billing and revenue cycle management. Data from the Centers for Medicare & Medicaid Services (CMS) shows that nearly 12% of cardiology claims are denied due to incomplete heart failure details. To avoid these errors, coders must bypass vague entries like I50.9 and document the exact patient status.

For instance, when a stable patient experiences a sudden flare-up, you should use the ICD 10 code for acute on chronic HFref (I50.23). Properly utilizing the specific ICD 10 code for HFrEF supports better risk-adjustment scoring and confirms that the patient meets the criteria for specialized disease-management programs. This level of detail protects your practice during audits and ensures patients receive the high-quality care they require.

What Are the Typical Symptoms of HFrEF That Coders Should Recognize?

To select the correct ICD 10 code for HFrEF, coders must recognize specific clinical symptoms that signal impaired heart function. Key indicators include:

  • Dyspnea on exertion
  • shortness of breath while lying flat (orthopnea)
  • swelling in the legs or feet.

These symptoms provide the "documentation anchors" required by the American Heart Association (AHA) and American College of Cardiology (ACC) to justify a diagnosis. Verifying these symptoms alongside an ejection fraction of 40% or less is essential when assigning the ICD 10 code for HFrEF.

Accurate symptom recording proves medical necessity for expensive tests like echocardiograms (CPT 93306). Without this link, insurance payers may deny claims for lacking clinical justification.

Clinical Symptom Documentation Expectation Coding Impact
Dyspnea on exertion Record exertional limitation and trigger activity level. Supports chronic HFrEF (I50.22) as defined by AHA/ACC guidelines.
Orthopnea or paroxysmal nocturnal dyspnea Note positional worsening of breathing during rest or sleep. Indicates pulmonary congestion consistent with I50.21 or I50.23 (acute or acute on chronic).
Peripheral edema Document severity, duration, and response to therapy. Correlates with volume overload that justifies IV diuretic therapy under CMS coverage rules.
Fatigue and reduced exercise tolerance Quantify in NYHA functional classes I-IV. Links directly to severity coding and risk adjustment validation.
Rapid weight gain / fluid retention Include daily weight monitoring details. Reinforces disease progression, often triggers repeat echo orders (CPT 93306).

Clear clinical notes, such as "EF 35% with peripheral edema," create a compliant path from diagnosis to reimbursement. This level of detail is necessary to avoid the 15% of cardiology claim denials caused by missing symptom data. By linking physical findings to the ICD 10 code for HFrEF, you ensure the highest first-pass approval rate.

What Is the ICD 10 Code for HFrEF and What Does It Mean?

The official ICD 10 code for HFrEF is classified under the I50.2x series, which specifically represents systolic heart failure. Clinical guidelines from the AHA and ACC define HFrEF as heart failure with an ejection fraction (EF) of 40% or less. Using a precise ICD-10-CM code for HFrEF is mandatory, as generic entries like "CHF" often trigger immediate claim denials during insurance audits.

For coding accuracy, you must distinguish between the different acuity levels of the condition. While I50.22 is the standard ICD 10 Code for HFrEF when the patient is stable, an exacerbation requires a more specific entry. In these cases, using the ICD 10 Code for acute on chronic HFrEF (I50.23) ensures the billing reflects the severity of the patient's current health status.

ICD-10 Code Description Documentation Requirement
I50.20 Unspecified systolic heart failure Use only when acuity (acute/chronic) is not documented. Avoid when EF and timeframe are known, as this may trigger specificity edits per CMS guidelines.
I50.21 Acute systolic heart failure Requires evidence of sudden decompensation; document symptoms such as pulmonary edema, orthopnea, or hospitalization for IV diuretics as per AHA standards.
I50.22 Chronic systolic heart failure Use when HFrEF is stable and the patient is maintained on guideline-directed medical therapy (GDMT). EF ≤ 40% should be clearly stated in the medical record.
I50.23 Acute on chronic systolic heart failure Used when a chronic patient experiences acute exacerbation. Documentation must specify baseline EF, current decompensation signs, and treatment response.

Selecting the correct code directly impacts your practice’s reimbursement and risk-adjustment scores. The Office of Inspector General (OIG) reports that over 18% of denied cardiology claims are due to a lack of specificity in heart failure coding. By avoiding unspecified codes like I50.20, you protect your facility from compliance risks and ensure accurate payment for services like BNP testing and device therapy.

Ensuring the medical record explicitly states the EF value and acuity level is the best way to support the ICD 10 code for HFrEF. If the documentation is vague, coders should query the physician to clarify whether the condition is acute or chronic. This level of detail is vital for meeting the "medical necessity" standards required by modern payer audits.

Which ICD-10 Chapter Includes HFrEF and Why Does That Matter for Sequencing?

The ICD 10 code for HFrEF (I50.2x) is found in Chapter IX: Diseases of the Circulatory System. This chapter covers all cardiovascular disorders and establishes the rules for how diagnoses are sequenced. Understanding this hierarchy is essential for accurate Diagnosis-Related Group (DRG) and ensuring insurance payers justify the medical necessity of the claim.

When coding for this condition, you must follow the "cause-and-effect" rule mandated by CMS. If a patient has both high blood pressure and heart failure, you cannot list the ICD 10 code for HFrEF as the primary diagnosis. Instead, you must code the underlying cause, such as hypertensive heart disease (I11.0), followed by the specific heart failure type.

ICD-10 Chapter Code Range HFrEF Placement Sequencing Guideline
Chapter IX: Diseases of the Circulatory System I00–I99 I50.2x – Systolic (HFrEF) Code the underlying cause first (e.g., hypertension, ischemic disease), followed by I50.2x per CMS sequencing rules.
Chapter I: Certain Infectious and Parasitic Diseases A00–B99 Rarely used in HF coding Use if heart failure is secondary to myocarditis due to infection, sequenced after infectious agent code.
Chapter XX: External Causes of Morbidity V00–Y99 Not applicable to HFrEF Use only if external trauma causes cardiac injury leading to failure.

Properly sequencing the ICD 10 code for HFrEF is a major factor in revenue cycle management and HCC risk adjustment. Incorrectly ordered codes often trigger automated payer edits, leading to down-coding or complete claim denials. Following these guidelines ensures that your clinical logic matches the official ICD-10-CM reporting requirements for 2026.

In complex cases, such as a sudden worsening of symptoms, you must still prioritize the root cause before adding the ICD 10 code for acute on chronic HFrEF. CMS reports that nearly 9.4% of heart failure claims fail due to poor sequencing or missing links between hypertension and heart failure. Maintaining these standards protects your practice from audits and ensures the patient's risk profile is correctly calculated.

Did You Know?
In its annual Improper Payment Measurement Report, CMS found that 9.4% of heart failure claims failed sequencing or linkage validations between hypertension and heart failure codes. These errors not only delayed payment but also triggered OIG audit referrals, making accurate sequencing a compliance imperative rather than a coding formality.

Which CPT Codes Pair with the ICD 10 Code for HFrEF?

To get paid correctly, you must pair the ICD 10 code for HFrEF with the right CPT codes. While the ICD-10 code for HFrEF explains the "why," the CPT code explains the "what" of the medical service. Proper linkage ensures that insurance payers see the clinical justification for expensive procedures and diagnostic tests.

In heart failure care, common procedures include imaging, blood work, and device implants. For example, a transthoracic echocardiogram (CPT 93306) is used to confirm that a patient has an ejection fraction of 40% or less. When you link this test to the ICD 10 code for HFrEF, it passes "medical necessity" filters and prevents automatic claim denials.

CPT Code Procedure Description Documentation Requirement
93306 Complete transthoracic echocardiography with Doppler and color flow study Must include EF measurement, ventricular function, and interpretation. Required for confirming HFrEF (EF ≤ 40%) per AHA/ACC guidelines.
93000 Electrocardiogram (ECG) with interpretation Record rhythm and conduction findings linked to HFrEF management (e.g., LBBB, atrial fibrillation).
83880 B-type natriuretic peptide (BNP or NT-proBNP) assay Document reason for test: differentiating dyspnea causes or monitoring HFrEF decompensation per CMS LCD policies.
33249 Insertion or replacement of transvenous ICD with defibrillation capability EF ≤ 35% after ≥3 months of GDMT; justification must reference 2026 AHA/ACC/HFSA criteria.
33225 LV lead placement for cardiac resynchronization therapy (CRT-D) Link to “LBBB with EF ≤ 35%, NYHA class II–IV,” per clinical guideline documentation.
99490 Chronic care management, ≥20 minutes per month Provider must document longitudinal management of chronic HFrEF and care coordination efforts, per CMS CCM program.

Mismatched codes are a leading cause of financial loss for cardiology practices. The Healthcare Financial Management Association (HFMA) notes that heart failure claims are denied 20% more often when the diagnosis and procedure are not linked properly. For instance, an implantable cardioverter-defibrillator (ICD) claim might be rejected if the ICD 10 code for acute on chronic HFrEF isn't sequenced correctly to show the patient's severity.

Beyond immediate payment, accurate linkage affects your long-term risk-adjustment (RAF) scores. If a high-value service like device implantation lacks an active ICD 10 code for HFrEF on the claim, the encounter may not count toward the patient's chronic disease burden. Ensuring every CPT code aligns with a specific HFrEF diagnosis protects your revenue and satisfies federal audit requirements.

Did You Know?
According to an OIG audit summary, nearly one in five cardiac device claims were denied or recouped due to missing or mismatched diagnostic justification, most often because the HFrEF ICD-10 code (I50.2x) was absent or improperly sequenced. ProMBS ensures that CPT 33249 and 93306 lines always align with I50.21, I50.22, or I50.23, satisfying both CMS coverage requirements and payer audit trails.

What Treatments Are Linked to HFrEF and How Should They Be Coded?

Treating Heart Failure with Reduced Ejection Fraction (HFrEF) focuses on improving heart function and preventing hospital stays. Modern care relies on GDMT, which includes specific medications and life-saving heart devices. To ensure proper reimbursement, clinical notes must link these treatments directly to the ICD 10 code for HFrEF to satisfy medical necessity.

Documentation should always mention the patient’s ejection fraction (EF) and their response to therapy. For example, starting a patient on specialized medications like SGLT2 inhibitors or ARNIs requires a documented EF of 40% or less. This data confirms the diagnosis and justifies the use of the ICD 10 code for HFrEF (I50.22) on medical claims.

Treatment Category Typical Clinical Documentation Coding and Billing Consideration
ARNI/ACEI/ARB Therapy “Started on sacubitril/valsartan per GDMT for HFrEF, EF 35%” Confirms EF ≤ 40% and guideline adherence, strengthens claim linkage with I50.22 (chronic HFrEF).
Beta-Blocker and MRA Therapy “Continuing carvedilol and spironolactone with stable symptoms” Supports chronic management and continuity of care billing (CPT 99490).
SGLT2 Inhibitors “Initiated dapagliflozin as add-on for HFrEF symptom control” Justifies prescription under heart failure coverage policy per CMS Part D guidance.
Device Therapy (ICD/CRT-D) “Meets criteria for CRT-D: EF 30%, LBBB, NYHA Class III” Documented under I50.23 with CPT 33249 + 33225 for device implantation.
Echocardiography Follow-Up “Repeat echo ordered to evaluate EF improvement post-therapy” CPT 93306 linked to I50.22 to confirm ongoing HFrEF monitoring.
Acute Decompensation Management “Admitted with acute on chronic HFrEF, IV diuretics, and oxygen therapy” Supports acute coding (I50.23) with CPT 99223–99233 for inpatient E/M services.

Accurate coding of these treatments prevents costly documentation mismatches that often trigger federal audits. The OIG frequently flags cardiac claims that lack a clear link between a device and the patient's ejection fraction. By clearly stating "EF 30% with stable HFrEF," you provide the evidence needed to support the ICD 10 code for HFrEF and avoid payment delays.

Finally, tracking these treatments helps boost your practice's overall revenue and efficiency. Research shows that practices with well-documented therapy plans experience 22% faster claim resolutions. Aligning every treatment - from a simple follow-up echo to a complex device implant - with the correct ICD 10 code for HFrEF ensures your billing remains compliant and audit-proof.

How Should Documentation Be Structured to Avoid Denials?

To avoid claim denials, your medical documentation must be structured with high specificity. The CMS frequently rejects heart failure claims that use vague terms like "CHF" or lack a measurable ejection fraction. To successfully bill the ICD 10 code for HFrEF (I50.2x), you must provide a clear clinical narrative that includes the patient's EF, their current disease phase, and the specific treatment plan.

According to AHIMA, a defensible medical record for heart failure requires three mandatory elements. First, you must list a quantifiable ejection fraction of 40% or less. Second, you must define the acuity - stating whether the condition is acute, chronic, or acute on chronic. Finally, you must link the ICD-10 code for HFrEF to a direct action, such as biomarker testing or a change in medication.

Documentation Gap Denial Trigger (with source) Corrective Strategy (with reference)
Missing EF data Claims fail coverage under the CMS LCD L34356 for heart failure diagnostics because EF confirmation is absent. Include “EF ≤ 40% confirmed by echo” per AHA/ACC Heart Failure Guidelines 2022.
Generic “CHF” without subtype Use of I50.9 violates specificity standards in the ICD-10-CM Official Guidelines FY 2026. Document and code explicitly as HFrEF or systolic heart failure (I50.2x) with acuity, following AHIMA documentation best practices.
CPT not linked to ICD-10 Procedures like 93306 or 33249 fail medical-necessity validation under CMS NCD Manual §20.33. Link all cardiology procedures to the corresponding I50.2x code, verifying pairings via the CMS NCCI Edit Table.
No documentation of treatment response Post-payment reviews under the OIG Work Plan FY 2026 cite “lack of follow-up outcome data.” Record EF trends and GDMT response per HFMA Revenue Integrity Report 2026.
Incomplete admission context DRG downgraded for “unspecified acute episode” during inpatient review per CMS MS-DRG Definitions Manual 2024. State: “Admitted for acute on chronic HFrEF requiring IV diuretics,” aligning with AHA inpatient coding guidance.

At ProMBS, every HFrEF claim passes through a three-tier documentation validation audit:

  • EF confirmation check (clinical accuracy)
  • Acuity and stage review (I50.21–I50.23)
  • ICD–CPT congruence verification (medical-necessity logic)

These checkpoints are part of our compliance-first RCM model that preempts denials before submission rather than reacting post-adjudication.

Did You Know?
The CMS Comprehensive Error Rate Testing (CERT) Report found that 42 percent of all cardiology denials stemmed from missing EF or acuity data. Practices using automated, reference-backed documentation audits, such as the ProMBS Denial Prevention Workflow, achieved a 96 percent first-pass acceptance rate and avoided downstream RAC recoupments.

Why Should Providers Partner with ProMBS for HFrEF Billing and Coding?

In cardiology, the difference between a paid claim and a denial depends on clinical precision. Partnering with ProMBS ensures that every ICD 10 code for HFrEF (I50.2x) is backed by expert documentation and audit-proof logic. Our cardiology-certified coders specialize in the specific requirements of the icd 10 CM Code for HFrEF, ensuring your practice captures the full clinical story while maximizing revenue.

The ProMBS Advantage for Cardiology Practices

  • Expert Clinical Validation: We verify essential details - like ejection fraction (EF) values and acuity descriptors - to ensure the ICD-10 code for HFrEF aligns with CMS and payer-specific guidelines.
  • Reduced Denial Rates: By using automated rule sets based on NCCI edit tables, we catch mismatched CPT-ICD combinations before they are submitted.
  • Precision in Complex Cases: We accurately manage the ICD 10 code for acute on chronic HFrEF (I50.23), ensuring high-acuity cases are billed for their true resource intensity.
  • Compliance-First Approach: Our teams continuously track updates from AHIMA and the OIG, shielding your practice from RAC audits and CERT recoupments.
  • Seamless CPT Linkage: We guarantee that high-value services, such as device implants or echocardiograms, are properly linked to the correct ICD 10 code for HFrEF.

ProMBS acts as a workforce extension, providing a dedicated team of HIPAA-compliant billing experts. We handle the complexities of the ICD 10 code for HFrEF, so your providers can focus on patient outcomes. With our digital audit trails and transparent reporting, you can grow your practice with the confidence that every claim is defensible and accurate.

Frequently Asked Questions

What is the exact ICD 10 code for HFrEF?
The specific ICD 10 code for HFrEF is the I50.2x series. This category identifies systolic heart failure where the ejection fraction is 40% or less. You must choose between I50.21 (acute), I50.22 (chronic), or I50.23 (acute on chronic) to ensure medical claims reflect the patient's true clinical status.

How do you code acute on chronic HFrEF?
Assign the icd 10 code for acute on chronic HFrEF (I50.23) when a patient with stable systolic dysfunction experiences a sudden flare-up. This code requires documentation of a reduced ejection fraction alongside new symptoms like pulmonary congestion. Using this specific code justifies higher-intensity treatments and prevents common billing denials.

Does the ICD-10-CM code for HFrEF require an ejection fraction value?
Yes, every ICD-10-CM code for HFrEF depends on a documented left-ventricular ejection fraction (LVEF) of 40% or lower. Payers and auditors look for this objective data to confirm medical necessity. Without a quantifiable EF value in the chart, insurance carriers often deny claims for "unspecified" heart failure.

Can I use the ICD-10 code for HFrEF as a primary diagnosis with hypertension?
No, official sequencing rules require you to code the underlying cause first. If a patient has hypertensive heart disease, you must list I11.0 as the primary diagnosis. You then report the icd-10 code for hfref as a secondary code to specify the type and severity of the heart failure.

Why do payers deny claims using the ICD 10 code for HFrEF?
Payers often deny these claims because of missing acuity details or mismatched CPT codes. Using the ICD 10 code for HFrEF without linking it to a specific procedure, like an echocardiogram or medication change, triggers medical necessity edits. Detailed documentation and precise code pairing remain the best defense against denials.